氟比洛芬酯复合舒芬太尼用于胸科手术后镇痛的临床观察

The Clinical Observation of Intravenous Analgesia with combined flurbiprofen axetil and sulfentanyl in patients after thoracic surgery

目的：观察氟比洛芬酯复合舒芬太尼用于胸科手术后静脉镇痛的效果.方法：择期行开胸手术患者60例,术后均行静脉镇痛,随机分为3组（n=20）.A组：舒芬太尼2μg/kg,生理盐水稀释至100ml;B组：舒芬太尼2μg/kg＋氟比洛芬酯100mg,生理盐水稀释至100ml：C组：舒芬太尼3μg/kg,生理盐水稀释至100ml.观察患者术后镇痛、镇静及不良反应情况.结果：在术后12、24小时的VAS评分中,B组与A组、C组与A组差异有统计学意义（P＜0.05）,术后12小时的VAFS评分中,B组与A组、C组与A组差异有统计学意义（P＜0.05）,术后12小时的White评分中,A组与C组、B组与C组差异有统计学意义（P＜0.05）.结论：氟比洛芬酯复合小剂量舒芬太尼用于胸科手术后镇痛更理想.

Objective： To observe intravenous analgesia effects of flurbiprofen axetil and sufentanyl on patient after thoracic surgery. Methods： Sixty patients undergoing thoracic surgery were randomized into three groups with 20 cases each. Group A ：sufentanil 2 μg / kg, diluted in NS 100ml. Group B ： sufentanil 2 μg / kg and flurbiprofen axetil 100 mg, diluted in NS 100ml. Group C：sufentanil 2 μg / kg, diluted in NS 100ml. The VAS score, VAFS score ,White score and side effect were recorded at 6, 12, 24, 36 hours after operation. Results ： The VAS scores of patients in group A was significantly higher than that in group B and group C at 12h, 24h after operation（ P 〈 0.05 ）. The VAFS scores of patients in group A was significantly higher than that in group B and group C at 12h after operation （ P 〈0. 05 ）. The White scores of patients in group C was significantly higher than that in group A and group B at 12h after operation （P 〈 0.05 ）. Conclusion： Flurbiprofen axetil combined low - dose sufentanil for analgesia after thoracic surgery is better.