肥胖对心肌梗死后患者峰值有氧工作能力的影响

The influence of adiposity on peak aerobic capacity in post myocardial infarction patients

目的:检测肥胖对心肌梗死后(PMI)患者心脏康复早期有氧工作能力的影响。方法:116例男性PMI患者根据其身体质量指数(BMI)高于或低于25和服用或未服用β-阻断剂被分为4组,然后进行递增负荷运动实验,其间记录每级负荷时的摄氧量(VO2)、心率(HR)、血压和自我用力感觉(RPE),并持续监测12导联心电图(ECG)。结果:BMI<25的两组患者都能坚持较长时间的运动(P<0.05),有较高的峰值摄氧量(P<0.05)和较低的有氧能力的损伤(P<0.01)。当RPE到达13时,其他组别的VO2分别是BMI<25且服用β-阻断剂组的90%(未服用β-阻断剂,BMI<25),75%(服用β-阻断剂,BMI>25)和70%(未服用β-阻断剂,BMI>25)。结论:肥胖会影响患者运动中的功能和代谢能力,但服用β-阻断剂对此可有所补偿。BMI<25对于减轻氧能力损伤将会有明显的益处。

Objective：To examine the influence of adiposity on the aerobic capacity of post myocardial infarction （PMI） patients during early stage of cardiac rehabilitation.Method：One hundred and sixteen male recent PMI patients were divided into four groups according to their body mass index （BMI） above or below 25,and with or without taking β-blocker.Then,a graded exercise test was performed;oxygen uptake （VO2）,heart rate （HR）,blood pressure and ratings of perceived exertion （RPE） were recorded,and 12 lead electrocardiogram （ECG） was monitored continuously.Result：Both groups with BMI25 could persist longer exercise time （P0.05）,had higher peak VO2 （P0.05）,and lower functional aerobic impairment （P0.01）.When RPE was at 13,relatively to the taking β-blocker and BMI25 group,the other groups had peak VO2 of 90% （no、β-blocker,BMI25）,75% （taking β-blocker,BMI25） and 70% （no β-blocker,BMI25） respectively.Conclusion：Adiposity can compromise patients＇ function and metabolic capacity during exercise,but in patients taking β-blocker there may be some compensation.One with BMI 25 will have particular benefits for alleviating functional aerobic impairment.