摘要
目的观察分析食管癌患者术后联合应用抗生素的利弊。方法回顾性分析273例食管癌患者的临床资料,根据术后抗生素应用情况分为单药组和多药组。统计分析患者术后严重感染和围术期并发症发生情况,比较组间差别。结果单药组135例患者与多药组138例患者相比,在胸腔感染、切口感染、吻合口瘘等并发症发生率差异无统计学意义(P>0.05),单药组患者腹泻发生率较多药组明显减少,差异有统计学意义(P<0.05)。结论食管癌术后应用单种抗生素预防感染安全有效,与联合应用抗生素相比无明显差异。
Objective To study the antibiotics application in postoperative period of esophageal cancer. Methods A retrospective analysis was conducted, and 273 patients were enrolled. According to the application of antibiotics after surgery, patients were divided into single -drug group and the multi -drug group. We compared and statistical analyzed the incidence of severe postoperative infection and complications between groups. Results 135 patients in single - drug group and 138 patients in multi - drug group. No significant difference exists in the incidence of chest infection, wound infection, anastomotic leakage and other complications. Conclusion It is safe and effective that using single antibiotics to prevent infection in postoperative period of esophageal cancer.
出处
《临床合理用药杂志》
2011年第05X期20-21,共2页
Chinese Journal of Clinical Rational Drug Use
关键词
食管癌
手术
抗生素
应用
Esophageal cancer
Operative
Antibiotics
Application
