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呋塞米持续静脉泵入治疗慢性心功能不全疗效分析与评价 被引量:1

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摘要 目的评价呋塞米持续静脉泵入治疗慢性心功能不全的疗效。方法 32例心功能不全经标准治疗及间歇静脉推注大剂量呋塞米治疗无效,改用呋塞米(20~40mg/h)经静脉持续泵入。观察新的给药方案后呋塞米的利尿效应、呼吸困难程度、全身水肿情况,监测体质量、血压、心率、血电解质和肾功能。结果经静脉持续泵入呋塞米10h后,连续5~10d,28例呼吸困难明显好转,全身水肿显著消退,尿量比治疗前显著增加,差异有统计学意义(P<0.01),体质量、心率、平均动脉压和血肌酐显著降低,差异均有统计学意义(P<0.05),血钾和血钠离子浓度无明显改变,差异无统计学意义(P>0.05)。血尿酸轻度升高。仅有4例症状缓解不明显。结论经静脉持续泵入呋塞米治疗慢性心功能不全安全有效。
出处 《临床合理用药杂志》 2011年第05X期50-51,共2页 Chinese Journal of Clinical Rational Drug Use
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