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胰腺癌基因治疗靶点研究现状 被引量:2

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摘要 胰腺癌具有高发病率和高死亡率的特点,并且是最难治疗的癌症之一。因此,迫切需要开展新的治疗方法。自1990年首次基因治疗临床试验以来,伴随分子生物学技术的进步,基因疗法得到了巨大的提高和空前的发展。在胰腺癌基因治疗过程中常采用外源基因的导入、表达,变异基因的修复,抑制转录,破坏癌变基因等方法来达到治疗目的,其中最关键的就是治疗靶点的选择。就近年胰腺癌基因治疗靶点研究成果与存在问题作一综述。
出处 《中国现代普通外科进展》 CAS 2011年第8期626-629,共4页 Chinese Journal of Current Advances in General Surgery
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