双氯芬酸、乙哌立松及甲钴胺联合治疗下腰痛的临床疗效分析

Clinical Effect of Low Back Pain after Triple Combination Therapy with Diclofenac,Eperisone and Methylcobalamin

目的：评价双氯芬酸、乙哌立松及甲钴胺联合用药治疗下腰痛的临床疗效。方法：收集我院2010年1月~2010年10月间门诊就诊的保守治疗下腰痛伴神经症状患者62例,应用双氯芬酸缓释片、乙哌立松及甲钴胺＂三联＂治疗,于治疗后第1、2、4周分别应用视觉模拟评分（VAS）和腰椎疾患疗效评分（JOA）评价疗效。结果：治疗1、2、4周后,所有患者临床症状不同程度改善。VAS及JOA评分在治疗1、2、4周后均较治疗前明显下降,差异有统计学意义（P〈0.05）,但治疗后3组1、2、4周之间比较差异无统计学意义（P〉0.05）。结论：双氯芬酸缓释片、乙哌立松及甲钴胺联合用药可以显著缓解下腰痛及神经症状,明显提高保守治疗患者生活质量且疗效满意。

Objective：To analysis the clinical effect of low back pain after triple combination therapy with diclofenac,eperisone,and methylcobalamin.Methods：A retrospective review was performed on 62 outpatients that diagnosis low back pain with neurological symptoms from Jan.2010 to Oct.2010 in our hospital.All cases treated with triple combination therapy with diclofenac,eperisone,and methylcobalamin.Clinical effect was evaluated by VAS and JOA scores 1,2,and 4 weeks after treatment.Results： The clinical symptoms of all patients were improved in varying degrees 1,2,and 4 weeks after treatment.The VAS and JOA scores were significantly decreased compared with before treatment（P0.05）,but there was no significant difference in the three groups after treatment（P0.05）.Conclusion：Combination therapy with diclofenac,eperisone,and methylcobalamin can be significantly alleviated the symptoms of low back pain and neurological symptoms.The conservative treatment can obviously improve the quality of patient＇s life and the results are satisfactory.