支原体肺炎患儿心肌酶改变的临床意义

The clinical significance about the change of myocardial enzymes in children with mycoplasma pneumonia

目的:探讨支原体肺炎患儿心肌酶的改变并分析其临床意义。方法:选择本院2008年1月～2010年1月收治的80例支原体肺炎患儿进行回顾性分析,其中25例支原体肺炎患儿的心肌酶(CK-MB)与肌钙蛋白(cTnI)增高;并与同期住院的15例病毒性心肌炎(MP-IgM阴性)患儿疗效对照比较。结果:本组25例婴幼儿支原体肺炎占同期住院支原体肺炎的72%(18/25),并且随着年龄的增长呈现减少趋势。治疗前后治疗组CK-MB和cTnI较对照组下降显著,差异有统计学意义(P<0.01)。结论:支原体肺炎发病年龄有小龄化的趋势,患儿除肺部改变外,常伴有心肌酶增高,发展为中毒性心肌炎。因此,治疗支原体肺炎时应监测心肌酶与肌钙蛋白的变化,以便早期发现肺外脏器损害并及时给予治疗。

Objective：To discuss the change of myocardial enzymes in children with mycoplasma pneumonia and analyze its clinical significance.Methods：80 mycoplasma pneumonia cases in our hospital from January 2008 to January 2010 were chosen and had been received retrospective studying.Among them,25 cases rose in CK-MB and cTnI.15 cases children with viral myocarditis（MP-IgM minus） who were in hospital within the same period been chosen.The treatment effects of the two groups were observed.Results：The 25 cases who were in hospital accounted for 72 percent（18/25）in the all children who were in hospital for mycoplasma pneumonia within the same period,and the phenomenon became less with the age growing.The CK-MB and cTnI dropped greatly of the treatment group than the contrasting group after the treatment,difference was statistically significant（P〈0.01）.Conclusion：The age of children who may get mycoplasma pneumonia is becoming low;The cases＇ CK-MB often rise besides the change of their lungs and developed into toxic myocarditis.So in order to find the damage of lungs early and treat it in time,we paediatricians should monitor the change of CK-MB and cTnI.