胸痛患者缺血修饰白蛋白的表达及其临床意义

Expression and clinical implication of ischemia-modified albumin in acute chest pain

目的:探讨缺血修饰白蛋白(IMA)对急性冠脉综合征(ACS)的诊断价值。方法:选本院心内科住院患者90例,男53例,女37例,平均年龄52.1岁,根据出院诊断分成3组,即急性心肌梗死(AMI)组、不稳定性心绞痛(UAP)组和非缺血性胸痛(NICP)组,另选同期来本院健康体检人群30例,其中,男18例,女12例,平均年龄46.00岁,作为健康对照组。分别检测各组IMA浓度,对比其对急性冠脉综合征的诊断效能。结果:ACS组的IMA值为(50.10±28.35)μg/L,明显高于NICP组(23.53±21.34)μg/L和健康对照组(20.30±11.05)μg/L,其差异有统计学意义(均P<0.05)。结论:IMA可用于疑似ACS的急性胸痛患者的早期诊断。

Objective：To investigate the value of ischemia modified albumin（IMA） in diagnosis of acute coronary syndrome.Methods：90 cases were chosen from our heart medicine inpatients.Among these patients,53 examples were males and 37 examples were females.The average age was 52.1years old.According to discharge diagnosis,patients with acute chest pain were divided into three groups,acute myocardial infarction（AMI） group,unstable angina pectoris（UAP） group and Non-ischemic chest pain（NICP） group.At the same time,we chose 30 cases healthy check-up people as healthy controls.18 examples were males and 12 examples were females.The average age was 46.00 years old.Through IMA concentration was detected respectively.Compared to its diagnostic efficiency for ischemic coronary syndrome.Results：The IMA concentrations of the ACS group（50.10±28.35） μg/L was obviously higher than the NICP group（23.53±21.34） μg/L and healthy controls group（20.30±11.05） μg/L,the difference was statistically significant（P〈0.05）.Conclusion：IMA can be used in the early diagnosis of ACS among the suspect patient with chest pain.