36例糖尿病酮症酸中毒急诊病例的临床研究

Clinical investigation of emergency treatment 36 cases with diabetic ketoacidosis

目的:探讨糖尿病酮症酸中毒(DKA)急诊病例的临床治疗方法。方法:把36例DKA患者随机分成两组,一组进行常规处理,另一组使用胰岛素泵治疗,密切观察两组的患者情况并监测血糖达标时间、尿酮转阴时间以及治疗前后血糖等指标变化情况,同时加强基础对症治疗。结果:使用胰岛素泵的治疗组,其血糖达标时间、血酮转阴时间和尿酮转阴时间明显优于常规治疗组(统计分析得P值均<0.01)。结论:胰岛素泵能够模拟胰岛素的生理分泌模式,更快、更有效地纠正酮症酸中毒患者的代谢紊乱,控制高血糖,可以取得比常规治疗组更加满意的疗效。

Objective：To investigate the clinical emergency treatment of diabetic ketoacidosis.Methods：The 36 patients with DKA were divided into two groups randomly.And one group underwent regular treatment,while another group underwent therapy with insulin pump.Then,the situation and time of blood glucose,urine ketone clearance time,and blood glucose were closely observed and monitored pre-therapy and post-therapy.Meanwhile,strengthen the basic symptomatic treatment were arranged.Results：The group underwent insulin pump therapy group show obvious advantages in the time of blood glucose reaching normal,and urine ketone clearance time compared with regular treatment group（P0.01）.Conclusion：Insulin pump can simulate the physiological insulin secretion pattern.Thus it can higher efficacy in correcting metabolic disorder and controlling high blood sugar in patients with ketoacidosis compared with regular treatment group.