转移性肝癌的血供对肝动脉化疗栓塞术疗效评价

Impact of blood supply on treating metastatic liver cancer with transcatheter arterial chemoembolization

目的探讨转移性肝癌的血供对肝动脉化疗栓塞术(TACE)的疗效。方法观察TACE治疗34例转移性肝癌的近期疗效和转移后生存率。结果转移性肝癌以乏血供为主,富血供组有效率为66.7%(8/12),乏血供组为31.8%(7/22),两组疗效差异有统计学意义(P<0.05)。富血供组6、12月转移后生存率分别为100%、75.0%,转移后中位生存期21.6月;乏血供组6、12月转移后生存率分别为81.8%、40.9%,转移后中位生存期13.5月,两组转移后中位生存期差异有统计学意义(P<0.05)。结论富血供的转移性肝癌治疗效果明显优于乏血供组。

Objective To investigate the impact of blood supply on treating metastatic hver cancer with transcatheter arterial chemoembolization （TACE）. Methods Clinical efficacy and survival rate were analyzed on 34 cases of metastatic liver cancer that were treated by TACE. Results Metastatic liver cancer was lack of blood supply-based. The values of CR ＋ PR in hypervascular group and lack of blood supply group were 66. 7% （8/12） and 31.8% （7/22） respectively,and the difference between the two groups was statistically significant （ P 〈 0. 05）. The survival rates of 6- and 12-month after metastasis in hypervascular group were 100% and 75. 0% respectively,while in lack of blood supply group were 81.8% and 40. 9% respectively. The medi- an survival periods after metastasis in hypervascular group and lack of blood supply group were 21.6 and 13. 5 months respective- ly, and the difference between the two groups was statistically significant （ P 〈 0. 05 ）. Conclusion TACE is significantly more effective for treating metastatic liver cancer with rich blood supply.