补肾促排卵汤预防多囊卵巢综合征患者卵泡黄素化疗效观察

Assistant Effect of Bushencupailtang on Preverting Luteinizing Unruptured Follicle Syndrome(LUFS)in Patients with Polycystic Ovary Syndrome(PCOS)

目的:观察补肾促排卵汤配伍人绒膜促性腺激素(HCG)预防多囊卵巢综合征(PCOS)促排卵中出现的卵泡未破裂黄素化综合征(LUFS)。方法:选择64例经促排卵后未破裂卵泡黄素化的多囊卵巢综合征患者,分为治疗组、对照组各32例,分别于卵泡成熟日治疗组用中药补肾促排卵汤及人绒膜促性腺激素(HCG)、对照组用人绒膜促性腺激素(HCG)治疗3个月经周期为1个疗程。观察患者黄体生成激素(LH)、雌二醇(E2)和孕酮(P)水平变化、排卵率及妊娠率。结果:治疗组升高LH、E2和P的作用优于对照组(P<0.05),排卵率及妊娠率均高于对照组(P<0.05)。结论:中药补肾促排卵汤配伍人绒膜促性腺激素(HCG)能预防PCOS促排卵中出现的LUFS,提高妊娠率,且无发生卵巢过度刺激综合征风险,值得推广。

Objective：To explore the effects of Bushen Cupailuan Decoction that can reinforce the kidney and activate blood circulation in treating patient with luteinized un-ruptured follicle syndrome（LUFS）.Methods：64 patients with the policy polycystic ovarian syndrome after facilitating ovulation appeared LUFS were divided into the treatment group and the control group.When the follicle matured,the treatment group was given Bushen Cupailuan Decoction and human chorionic gonadotropin（HCG）while the control group was given HCG for the Period of treatment.Before and after 30 hours HCG injection LH、E2 and P were detected in Both group.Results：The treatment group had a better effect on improving the LH and P and E2 levels,the ovulation percentage and the gestation percentage than the control group（P0.05）.Conclusions：Bushen Cupailuan Decoction that can reinforce the kidney and activate blood circulation have better effects in patients with LUFS without the ovarian hyperstimulation syndrome and it is a method worth popularizing.