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生长激素释放肽(ghrelin)促生长作用和应用前景 被引量：2

Ghrelin: Effect on Growth Promotion and Application Prospects
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摘要 生长激素释放肽(ghrelin)是在大鼠和人胃内发现的,是一种生长激素促分泌素受体(growth hormone secretagogue receptor,GHSR)的内源性配体。ghrelin与位于垂体、下丘脑的GHSR结合后,具有促进生长激素释放、增加食欲、调节消化系统功能和能量代谢等作用。本文对ghrelin的结构、分布、生物学功能的近期研究成果及畜牧业上的应用前景进行综述,以期为相关添加剂的研究和开发提供依据。 Ghrelin,a peptide puried from rat and human stomachs,is an endogenous ligand for the growth hormone secretagogue receptor（GHSR）.Ghrelin,after binding with GHSR in the hypothalamus and pituitary,not only promotes the GH releasing and increases appetite,but also adjusts the functions of digestive system and energy metabolism.This article mainly reviewed the recent developments on structure,distribution and biological functions of ghrelin as well as its potential applications on animal husbandry,which may lay the foundation for research and development of related additives.
作者 来景辉 范红结
机构地区 宿州职业技术学院动物科学系 南京农业大学动物医学院
出处 《动物营养学报》 CAS CSCD 北大核心 2011年第7期1085-1088,共4页 CHINESE JOURNAL OF ANIMAL NUTRITION
关键词 生长激素释放肽 生长激素促分泌素受体 生物学功能 ghrelin growth hormone secretagogue receptor biological function
分类号 S852.2 [农业科学—基础兽医学]
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参考文献15

  • 1KOJIMA M, HOSODA H, DATE I, et al. Ghrelin is a growth hormonereleasing acylated peptide from the stomach [J].Nature, 1999, 402:656 - 660.
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二级参考文献22

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动物营养学报
2011年 第7期

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