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化生性胸腺瘤临床病理分析及文献复习 被引量:1

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摘要 目的探讨化生性胸腺瘤的临床病理学和生物学行为特点。方法对2例纵隔化生性胸腺瘤进行临床特征、组织病理形态学、影像诊断学和免疫组化研究,并复习相关文献。结果 2例患者均为男性,分别为35、38岁,CT提示前纵隔占位,境界清楚。组织学表现为典型的双相性表现,上皮细胞区域和梭形细胞区域交错分布,间质散在少许淋巴细胞,肿瘤细胞无明显异型性。免疫表型:上皮细胞区域Ckpan(+),CD5(-),梭形细胞区域Vimentin(+),Ckpan(-)。结论化生性胸腺瘤是一种少见的肿瘤,有着与普通胸腺瘤截然不同的组织学形态,肿瘤一般无复发或转移,是一种恶性潜能较低的胸腺瘤亚型。
出处 《江苏医药》 CAS CSCD 北大核心 2011年第17期2074-2075,F0003,共3页 Jiangsu Medical Journal
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参考文献5

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  • 5李旭,石怀银.化生性胸腺瘤1例[J].临床与实验病理学杂志,2007,23(2):252-253. 被引量:8

二级参考文献9

  • 1Suster S, Moran CA, Chan JK. Thymoma with pseudosarcomatous stroma: report of an unusual histologic variant of thymic epithelial neoplasm that may simulate carcinosarcoma. Am J Surg Pathol,1997, 21:1316-1323.
  • 2Yoneda S, Marx A, Heimann S, et al. Low-grade metaplastic carcinoma of the thymus. Histopathology, 1999,35 : 19-30.
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共引文献15

同被引文献20

  • 1金梅,刘标,王丽,许敬尧.化生性胸腺瘤临床病理分析[J].中华病理学杂志,2006,35(5):285-288. 被引量:14
  • 2方志欣,毛志福,林辉,韦海明.胸腺上皮肿瘤WHO新组织学分型与临床特征的相关性分析[J].广西医学,2006,28(10):1523-1525. 被引量:1
  • 3李旭,石怀银.化生性胸腺瘤1例[J].临床与实验病理学杂志,2007,23(2):252-253. 被引量:8
  • 4Suster S, Moran C A, Chan J K. Thymoma with pseudosarcoma- tous stroma: report of an unusual histologic variant of thymic epi- thelial neoplasm that may simulate carcinosarcoma[ J]. Am J Surg Pathol, 1997, 21(11) :1316 -23.
  • 5Travis W D, Brambilla E, Miiller-Hermelink H K, et al. World Health Organization classification of tumours pathology and genet- ics. Tumours of the lung, pleura, thymus and heart [ M ]. Lyon : LARC Press, 2004:146-7.
  • 6Yoneda S, Marx A, Heimann S, et al. Low-grade metaplastic car- cinoma of the thymus [ J]. Histopatholo.gy, 1999,35 ( 1 ) : 19 - 30.
  • 7Yoneda S, A Marx A, Miiller-Hermelink H K. Low-grade meta- plastic carcinomas of the thymus : biphasic thymic epithelial tumors with mesenchymal metaplasia-an update [ J ]. Pathol Res Pract, 1999,195(8) :555 -63.
  • 8Noh T W, Kim S H, Lira B J, et al. Thymoma with pseudosarcom- atous stroma[ J ]. Yonsei Med J, 2001 ,42 (5) :571 - 5.
  • 9Moritani S, Ichihara S, Mukai K, et al. Sarcomatoid carcinoma of the thymus arising in metaplastic thymoma [ J ]. Histopathology, 2008,52(3) :409 - 11.
  • 10Poorabdollah M, Mehdizadeh E, Mohammadi F, et al. Metaplastic thymoma: report of an unusual thymic epithelial neoplasm arising in the wall of a thymic cyst [ J]. Int J Surg Pathol, 2009,7 ( 1 ) :51 -4.

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