1Gutierrez-Adrianzen Oa, Fau-Koutouzov S, Mota RM, et al. Di- agnostic value of anti-nucleosome antibodies in the assessment of disease activity of systemic lupus erythematosus: a prospective study comparing anti-nucleosome with anti-dsDNA antibodies [J]. J Rheumatol, 2006, 33(8): 1538-1544.
2Ng KP, Manson JJ, Rahman A, et al. Association of antinucleo- some antibodies with disease flare in serologically active clini- cally quiescent patients with systemic lupus erythematosus[J]. Arthritis Rheum, 2006, 55(6): 900-904.
3Wellmann U, Letz M, Herrmann M, et al. The evolution of hu- man anti-double-stranded DNA autoantibodies [J]. Proc Natl A- cad Sci, 2005, 102(26): 9258-9263.
4Bendiksen S, Van Ghelue M, Winkler T, et al. Autoimmunity to DNA and nucleosomes in binary tetracycline-regulated poly- omavirus T-Ag transgenic mice[J]. J Immunol, 2004, 173(12): 7630-7640.
5Medzhitov R, Janeway CA Jr. Decoding the patterns of self and nonself by the innate immune system[J]. Science, 2002, 296 (5566): 298-300.
6Mortensen ES, Fenton KA, Rekvig OP. Lupus nephritis: the cen- tral role of nucleosomes revealed[J]. Am J Pathol, 2008, 172(2): 275-283.
7Matzinger, P. Friendly and dangerous signals: is the tissue in control?[J]. Nat hnmunol, 2007, 8(1): 11-13.
8Gaipl US, Voll RE, Sheriff A, et al. Impaired clearance of dy- ing cells in systemic lupus erythematosus [J]. Autoimmun Rev, 2005, 4(4): 189-194.
9van Bruggen MC, Walgreen B, Rijke TP, et al. Antigen speci- ficity of anti-nuclear antibodies complexed to nucleosomes deter- mines glomemlar basement membrane binding in vivo[J]. Eur J Immunol, 1997, 27(6): 1564-1569.
10Grootscholten C, van Bruggen MC, van der Pijl JW, et al. De- position of nucleosomal antigens (histones and DNA) in the epi- dermal basement membrane in human lupus nephritis[J]. Arthritis Rheum, 2003, 48(5): 1355-1362.
