期刊文献+

血液净化在危重症感染治疗中的作用研究 被引量:4

下载PDF
导出
摘要 目的观察研究血液净化治疗在危重症感染中的疗效作用和作用机制。方法将36例重症感染(重症脓毒血症)患者采用随机数字表法分为两组:试验组和对照组,每组18例。对照组采用常规对症支持治疗,在此基础上试验组行连续肾替代疗法(CRRT)治疗。观察两组患者治疗中APA-CHEII评分及乳酸、细胞间粘附分子(intercellular adhesion molecule 1,ICAM-1)的变化等情况。结果试验组有效率明显高于对照组(均P<0.05)。试验组APACHEII评分、APACHII评分及乳酸、CRP、细胞间粘附分子的变化与对照组比较差异均有统计学意义。结论 CRRT治疗重症感染(重症脓毒血症)有较好的效果,与清除炎症介质的表达有关。
出处 《齐齐哈尔医学院学报》 2011年第16期2611-2612,共2页 Journal of Qiqihar Medical University
  • 相关文献

参考文献12

  • 1姚咏明,盛志勇.重视对脓毒症本质的探讨[J].中华急诊医学杂志,2005,14(3):185-186. 被引量:118
  • 2Levy MM,Fink MP,Marsha II JC,et al. 2001 SCCM/ESICM/ ACCP/ATS/SIS international sepsis definitions conference [J]. Crit Care Med,2003,31:1 250-- 1 256.
  • 3Shaprio N, Howell MD, et al. The association of sepsis syn- drome and organ dysfunction with mortality in emergency de- partment patients with suspected infection[J].Ann Emerg M 额定 ,2006,48(5) :583--590.
  • 4Kleinpell RM, Grabes BT, Ackerman MH. Incidence, patho genesis,and management of sepsis; an overview~J~. AACN Adv Crit Care, 2006,17(4) :385--393.
  • 5Angus DC, Linde-- Zwinble WT, Lidicker J, et al. Epidemiology of severe sepsis In the United States:analysis of incidence, out-- come,and associated costs of care[J]. Crit Care Med, 2001,29 (5) :1 303--1 310.
  • 6Nguyen HB, Rivers EP, Abrahamiam FM, et al. Severe sepsis and septic shock: review o{ the literature and emergency de partment management guidelines[J]. Ann Emerg Med, 2006, 48:28--54.
  • 7Peng Y,Yuan Z, Li H. Removal of inflamyatory cytokines and endotoxin by veno--venous continuous renal replacement ther- apy for burned patients with sepsis[J]. Burns, 2005,31 (5):623--628.
  • 8季大玺,谢红浪,龚德华.连续性血液净化在多器官功能障碍综合征中的应用[J].肾脏病与透析肾移植杂志,2001,10(2):176-181. 被引量:73
  • 9管向东,寇秋野.感染性休克血流动力学的监测指标[J].创伤外科杂志,2007,9(2):97-99. 被引量:28
  • 10Corely KT, Donaldson LL, Furr MO. Arterial lactate concen tration,hospital survival, sepsis and SIRE in critily ill neonatal foals[J]. Equine Vet J, 2005,37 :53-- 59.

二级参考文献47

共引文献218

同被引文献57

  • 1王今达,王宝恩.多脏器功能失常综合征(MODS)病情分期诊断及严重程度评分标准(经庐山’95全国危重病急救医学学术会讨论通过)[J].中国危重病急救医学,1995,7(6):346-347. 被引量:1415
  • 2林锡芳,江松福,叶进燕,潘景业,王丹,吴建波,林碎钗,施怡声.连续性血液净化在脓毒症并多脏器功能不全治疗中的应用[J].温州医学院学报,2005,35(6):486-488. 被引量:4
  • 3管向东,寇秋野.感染性休克血流动力学的监测指标[J].创伤外科杂志,2007,9(2):97-99. 被引量:28
  • 4Kramer N,Meyer TJ,Meharg J,et a1.Randomized pro-spective trial of noninvasive positive pressure ventilationin acute respiratory failure[J].Am J Respir Crit CareMed,1995,151(6):1799-1806.
  • 5American College of Chest Physician s/Society of Criti-cal Care Medicine Consensus Conference:definitions forsepsis and organ failure and guidelines for the use of in-novative therapies sepsis[J].Crit Care Med,1992,20(6):864-874.
  • 6Shapiro N,Howell MD,Bates DW,et a1.The associa-tion of sepsis syndrome and organ dysfunction withmortality in emergency department patients with sus-pected infection[J].Ann Emerg M,2006,48(5):583-590.
  • 7Kleinpell RM,Grabes BT,Ackerman MH.Incidence,pathogenesis,and management of sepsis;an overview[J].AACN Adv Crit Care,2006,17(4):385-393.
  • 8Angus DC,Linde-Zwinble WT,Lidieker J,et a1.Epide-miology of severe sepsis In the United States:analysisof incidence,outcome,and associated costs of care[J].Crit Care Med,2001,29(5):1 303-1 310.
  • 9Corely KT,DonaldsonⅡ,Furr M.Arterial lactate con-centration,hospital survival,sepsis and SIRE in critilyneonatalfoals[J].Equine Vet J,2005,37:53-59.
  • 10Price S,Anning PB,Mitchell JA,et al.Myocardial dysfunction insepsis:mechanisms and therapeutic implications[J].Eur Heart J,1999,20(10):715-724.

引证文献4

二级引证文献54

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部