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可溶性间皮素相关蛋白和癌抗原125联合检测在卵巢癌诊断中的价值 被引量:4

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摘要 目的探讨联合检测血清可溶性间皮素相关蛋白(SMRP)和癌抗原125(CA125)在卵巢癌诊断中的价值。方法入选30例卵巢癌(卵巢癌组)、30例卵巢良性肿瘤(卵巢良眭肿瘤组)及30例健康志愿者(对照组),采用酶联免疫吸附法和化学发光法分别检测血清SMRP和CA125水平。结果卵巢癌组血清CA125和SMRP水平均显著高于卵巢良性肿瘤组和对照组(P〈0.05)。单独检测SMRP的敏感度和特异度分别为90.0%(27/30)和93.3%(28/30),单独检测CA125均为86.7%(26/30),两者平行联合检测分别为93.3%(28/30)和83.3%(25/30),两者系列联合检测分别为83.3%(25/30)和96.7%(29/30)。结论卵巢癌患者血清SMRP和CA125的表达呈一致性升高,两者联合检测更有助于卵巢癌的诊断,具有较好的临床应用价值。
出处 《中国医师进修杂志》 2011年第27期50-51,共2页 Chinese Journal of Postgraduates of Medicine
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