^(131)I治疗分化型甲状腺癌颈部软组织转移的临床分析

Clinical analysis of cervical soft tissue metastasis of differentiated thyroid cancer with ^(131)I treatment

目的分析分化型甲状腺癌(DTC)术后患者颈部软组织转移特点及大剂量^(131)I治疗效果。方法回顾2001年至2010年在本科接受^(131)I治疗的122例DTC术后患者,其中13例(10.7%)合并颈部软组织转移灶。结果 13例领部软组织转移与109例无颈部软组织转移患者存在远处转移的比例分别为48.1%和25.8%(P<0.05);大剂量^(131)I治疗颈部软组织转移治愈率、有效率和无效率分别为37.4%、58.3%和4.3%。结论 DTC术后颈部软组织转移合并远处转移的可能性较高;大剂量^(131)I治疗颈部软组织转移疗效显著。

Objective To analyze the characteristics of cervical soft tissue metastasis in postoperative of differentiated thyroid cancer and the effect of high dose ^131I treatment. Methods There were 122 patients in postoperative of DTC received ^131I treatment from 2001 to 2010 in our sections, of which 13 cases （10.7%） combined with cervical soft tissue metastasis. Results The percentage of distant metastasis in 13 cases with cervical soft tissue metastasis and 109 cases with non-existence were 48.1% and 25.8% （P〈 0.05 ） .The cure rate, effective rate and ineffective rate of cervical soft tissue metastasis with high dose ^131I treatment were 37.4%, 58.3% and 4.3%. Conclusion Cervical soft tissue metastasis in postoperative of DTC usually combined with distant metastasis. High dosage of ^131I therapy has rather powful effects on cervical soft tissue metastasis in postoperative of DTC.