十五元三烯大环的合成及其改性聚丙烯亚胺

Synthesis of 15-Membered Triolefinic Macrocycles and Its Application in the Modification of Poly(propyleneimine)

以1,4-二溴-2-丁烯、4-氟苯磺酰胺、2,4,6-三异丙基磺酰胺为主要原料,采用5步法合成一种含氮的十五元三烯大环化合物———(E,E,E)-1,6-二[(2,4,6-三异丙基苯基)磺酰基]-11-[(4-氟苯基)磺酰基]-1,6,11-三氮环十五烷-3,8,13-三烯。进而使用十五元三烯大环化合物改性2.0代的聚丙烯亚胺树状聚合物(2.0G PPI,实验室自制)的外围基团,制备聚丙烯亚胺杂化树型聚合物。利用核磁共振波谱和红外光谱表征了中间产物和目标产物的结构,结果表明,所得中间产物和目标产物均符合分子设计要求,合成路线合理可行。

A type of nitrogen-containing 15-membered triolefinic macrocycles （ E, E, E ） -1,6-bis [ （2,4,6-triiso-propylphenyl） sufonyl ] -11- [ （ 4-fluorophenyl ） sulfonyl ] -1,6, i i -triazacyclopentadeca- 3,8,13-triene was synthesized with 1,4-dibromo-2-buten, 4-fluorobenzenesulfonamide, and 2,4,6- triisopropylbenzenesulfonamide as the main reactants. The periphery group of the 2. 0 generation poly （propyleneimine） dendrimer（2.0G PPI）,which was prepared by the co-worker of the laboratory, was modified by the 15-membered triolefinie macrocyclic compounds to synthesize hybrid poly （propyleneimine） dendrimer. The products were proved to be in accord with the theoretical structure by characterization with infrared and nuclear magnetic resonance spectroscopy.