氢化物发生-原子荧光法测定三七、三七三醇皂苷及其制剂中的砷

Determination of the Arsenic in Notoginseng Radix et Rhizoma,Panaxatriol Saponins and its Preparation by Hydride Generation Atomic Fluorescence Spectrometry

目的:研究三七、三七三醇皂苷(PTS)及其制剂三七通舒胶囊中的重金属砷(As)的检测方法及含量。方法:采用微波消解-氢化物发生-原子荧光法进行测定As,系统地研究微波消解、氢化物发生的最佳条件。结果:荧光强度与进样浓度之间呈良好的线性关系,线性范围0～12μg.L-1,回收率为88.37%～104.76%,检出限0.109 6μg.L-1,RSD为0.82%,PTS及其制剂中As含量较低。结论:该方法具有简便、快速、灵敏度高等优点,适用于三七、PTS及其制剂中As的测定。

Objective：To determine the content of Arsenic（As）in radix notoginseng,panaxatriol saponins（PTS）and Sanqi Tongshu capsule.Method： The content of As was determined by hydride generation atomic fluorescence spectrometry.The optimal experimental conditions of microwave digestion-hydride generation were optimized.Result： Fluorescence intensity and concentration was in a good linear relationship;the linear range was0-12 ng·mL-1and the recovery was in the range of 88.37%-104.76%,the detection limit was 0.109 6 ng·mL-1,RSD 0.82%;the content of As in PTS and its preparation were low.Conclusion：The method was simple,rapid and high sensitive.It can be used in the determination of As in radix notoginseng,protoparaxotriol saponins and its preparation.