慢性肝病血清LN与白、球蛋白含量变化的关系研究

The relationship study on the changes of sera LN and ALB/GLO in patients with chronic liver diseases

目的:研究慢性肝病血清层粘蛋白(LN)与白、球蛋白含量变化的关系。方法:对177例慢性肝病患者采用化学发光法测定血清LN含量,采用全自动生化分析仪AU5400检测血清白蛋白和球蛋白的含量。结果:慢性肝病患者血清LN含量显著高于正常人群(P<0.01),以LN大于等于130 ng/ml和小于130 ng/ml将患者分为两组,二者白蛋白和球蛋白含量比较差异高度显著。结论:血清LN变化与慢性肝病病情严重程度关系密切。

Objective： To study the relationship between the changes of sera LN and ALB/GLO in patients with chronic liver diseases.Methods： Sera LN was detected by chemiluminescence immune detection system and sera ALB/GLO were detected by AU 5400 in 177 cases with chronic liver diseases.Results： The concentration of LN in patients with chronic liver disease is significantly higher than that of healthy individuals（P0.01）. The 177 patients were divided into two groups according to the LN level above or below 130 ng/ml,it was found that there was significant difference between the level of ALB and GLO.Conclusion： There is a good relationship between LN and the severity of the patient with chronic liver disease.