地奥司明片治疗急性发作痔92例临床分析

Diosimin Tablet in the Treatment of Acute Hemorrhoids：Clinical Analysis of 92 Cases

为观察地奥司明片对痔急性发作症状的I临床疗效，将146例痔患者分为两组，治疗组92例给予地奥司明片治疗，对照组54例给予痔速宁片治疗，对照观察两组药物对疼痛、便血、水肿、黏膜改变的时效和疗效。结果显示，治疗组对疼痛、便血的平均起效时间分别为（15．0±1．21）h和（25．0±2．33）h，症状消除时间分别为（3．7±1．2）d和（4．4±1．5）d，对照组疼痛、便血的平均起效时间分别为（22．0±0．84）h和（36．0±1.57）h，症状消除时间分别为（5．1±1．2）d和（5．6±1．2）d，治疗组优于对照组（P〈0．05）。7d后便血、黏膜改变的分值下降，治疗组优于对照组（P〈0．05），治疗组和对照组显效率分别为69．6％和48．1％（P〈0．05）。结果表明，地奥司明片治疗痔急性发作起效快，疗效显著。

The objecitve of the study was to observe the therapeutic efficacy of Diosimin tablet in the treatment of acute hemorrhoids. One hundred and forty six patients wiht this disease were divided into two groups,patients in the study group（ n = 92） received Diosimin tablet treatment, while patients in the control group（ n =54） received Zhisuning tablet for treatment. As results,the mean starting time of analgesia and bloody stool cease in the study and control groups was （15.0±1. 21） hours vs （22.0!0.84） hoursl （25.0±2.33） hours vs （36.0±1.57） hours （ P 〈0.05）,and the symptoms subsiding time was （3.7±1.2） days vs （5.1±1.2） days; （4.4±1.5） days vs （5.6±1.2） days （P〈0.05） all better than the control group;the scores of bloody stool and mucosa change declined 7 days after treatment in the two groups, while the score was less in the study group（ P 〈0.05）;the marked improvement rate in the two groups was 69.6% vs 48.1%（ P 〈0.05）. It is concluded that Diosimin tablet is better in terms of quickness in efficacy start and therapeutic efficacy significant in the treatment of acre phase of hemorrhoids.