摘要
目的了解医院尿液标本中大肠埃希菌(ECO)的临床分布及耐药性,为临床合理使用敏感抗菌药物提供依据。方法回顾性分析2010年4月~2011年2月间尿液标本中分离的161株大肠埃希菌的临床分布及耐药性。结果 161株大肠埃希菌主要来自泌尿内科(62.7%)、重症监护病房(13%)及内科病房(10%)。药敏结果显示对亚胺培南、美罗培南、厄他培南、哌拉西林/他唑巴坦、头孢西丁、头孢吡肟、头孢他啶、氨曲南、阿莫西林/棒酸、头孢噻肟、妥布霉素、庆大霉素、左氧氟沙星、环丙沙星、复方新诺明、头孢唑啉、呋喃妥因和氨苄西林的耐药率分别为0.00%0、.00%0、.00%5、.6%1、6.8%、23%、26.7%、33.5%、43.5%、48.4%、50.9%、52.8%、60.9%、62.1%、73.9%、80.7%、90.1%和92.5%。结论大肠埃希菌为泌尿道感染的常见病原菌,有效地控制由其造成的感染临床上应根据耐药特点合理选用抗生素。
Objective: To investigate drug resistance and clinical distribution of E.coli isolated from urine in hospital,and to provide the guidance for the rational clinical application of antibiotics.Methods:161 strains of E.coli were isolated from urine from June 2010-February 2011,whose drug resistance rates and clinical distribution were analyzed retrospectively.Results: 161 strains of E.coli were collected mainly from the Department of Urology(62.7%),Intensive Care Unit(13%) and Medical Wards(10%).Resistance rates to imipenem,meropenem,ertapenem,piperacillin/tazobactam,cefoxitin,cefepime,ceftazidime,aztreonam,amoxicillin/clavulanic,cefotaxime,tobramycin,cidomycin,levofloxacin,ciprofloxacin,SMZ-TMP,cefazolin,furadantin and ampicillin were 0.00%,0.00%,0.00%,5.6%,16.8%,23%,26.7%,33.5%,43.5%,48.4%,50.9%,52.8%,60.9%,62.1%,73.9%,80.7%,90.1% and 92.5%.Conclusion: E.coli is common pathogen which can cause urinary tract infection and the antibiotics should be chosen according to drug sensitivity test in the clinical practice.
出处
《泰山医学院学报》
CAS
2011年第7期524-526,共3页
Journal of Taishan Medical College
关键词
大肠埃希菌
泌尿道感染
临床分布
耐药性
Escherichia coli
urinary tract infection
clinical distribution
drug resistance