支气管肺炎患儿治疗前后血清IGF-Ⅱ,hs-CRP和M-CSF水平检测的临床意义

Measurement of changes of serum IGF-Ⅱ,hs-CRP and M-CSF levels after treatment in pediatric patients with bron-chopneumonia

目的探讨支气管肺炎患儿治疗前后血清IGF-Ⅱ,hs-CRP和M-CSF水平的变化及意义。方法应用放射免疫分析法和免疫比浊法对32例支气管肺炎患儿进行治疗前后血清IGF-Ⅱ,hs-CRP和M-CSF水平测定。并与32名正常健康儿作比较。结果在治疗前,支气管肺炎患儿治疗前后血清IGF-Ⅱ,hs-CRP和M-CSF水平非常显著地高于正常人组(P<0.01),经治疗1周后则与正常人比较无显著性差异(P>0.05)。结论检测支气管肺炎患儿治疗前后血清IGF-Ⅱ,hs-CRP和M-CSF水平的变化对疾病的诊断、治疗和预后的判断均具有十分重要的价值。

Objective To explore the clinical significance of changes of serum IGF-Ⅱ,hs-CRP and M-CSF levels after treatment in pediatric patients with bronchopneumonia.Methods Serum IGF-Ⅱ,M-CSF（with RIA）and hs-CRP（with immunolurbidity method） levels were determined in 32 pediatric patients with bronchopneumonia both before and after treatment as well as in 35 controls.Results Before treatment,serum IGF-Ⅱ,hs-CRP and M-CSF levels in the patients were significantly higher than those in the controls（P0.01）.One week after treatment,serum IGF-Ⅱ,hs-CRP and M-CSF levels were not significantly different from those in the controls（P0.05）.Conclusion Determination of serum IGF-Ⅱ,hs-CRP and M-CSF levels in pediatric patients with bronchopneumonia is important for diagnosis and outcome prediction.