纳米颗粒暴露评价研究综述

Review on Nanoparticle Exposure Assessment Research

对国外最新的人造纳米颗粒的暴露评价方法和研究结果进行综述,旨在为我国今后工作现场的职业卫生暴露评价提供指导。检索和查阅2000—2010年发表的涉及纳米颗粒暴露评价的同行评审期刊的英文文献和报告,并对暴露评价设备和方法进行比较和分析,归纳描述部分研究结果,总结纳米颗粒暴露评价的特殊性和挑战,探讨解决这些问题的关键步骤。最后,提出今后在职业现场开展纳米暴露评价的2个可行的方法。

The purpose of this article is to make a literature review on the current knowledge and progress in nanoparticle exposure assessment at abroad,and provides guidance for occupational exposure assessment of nanoparticles in China in future.Firstly,English journal articles and reports published between 2000 and 2010 were collected and reviewed.Then comparisons and analysis were made on the exposure assessment devices and methods used by these studies,and their research findings were summarized.In addition,specialty and challenges to conduct nanoparticles exposure assessment were discussed and the key steps to solve those issues were presented.Finally,two possible approaches to perform field exposure assessment of nanoparticles in future were proposed.