摘要
目的对比不同发病年龄的强迫症患者的临床特点和认知功能，尝试探讨疾病的分型。方法纳入强迫症患者140例，采用一般资料、耶鲁布郎强迫量表、社会功能缺陷筛选量表、汉米尔顿焦虑和抑郁量表评定临床特点，以及连线测验、河内塔测验、Rey复杂图、数字倒背、言语流畅性测验评价认知功能。以发病年龄18岁为早晚发的分界线，进行对比。结果发病年龄小于18岁组患者（n=93）与发病年龄大于18岁组患者（n=47）相比，间断痫程、自杀观念多[（x2=4．214）（x。：11．542）]，差异具有显著性（P〈0．05）。发病年龄小于18岁组患者连线测验连线时间短，出错的次数少[（81．696±50．172）次，（109．114±48．070）次；（1，169±2．983）次，（1．405±2．020）次]，差异具有显著性（P〈0．05）。结论不同发病年龄的强迫症可能是不同的疾病亚型。
Objective To compare the clinical feature and cognitive function between patients with obsessive-compulsive disorder of different onset age and explore possible subtype. Methods 140 Patients with obsessive-compulsive disorder （OCD） were enrolled in test. All finished a series of tests including clinical feature, Trail-making test （TMT） , Tower of Hanoi （TH） and Word fluency test （WFT）. Patients were divided into two groups by onset age of 18. Results Compared with patients of onset age after18, patients of onset before 18 were more with episode duration and more suicide attitude （ X2 = 4.214, X2 = 11. 542, P 〈 0.05 ）. In TMT patients of onset before 18 had shorter time and little errors（ （81. 696 ± 50. 172 ）vs （109.114 ± 48. 070 ）, （1. 169 ± 2. 983 ）vs （ 1. 405 ± 2. 020）, P 〈 0.05 ）. Conclusion Obsessive-compulsive disorder with different onset age may be different type.
出处
《中华行为医学与脑科学杂志》
CAS
CSCD
北大核心
2011年第9期824-826,共3页
Chinese Journal of Behavioral Medicine and Brain Science
关键词
强迫症
临床特点
认知功能
Obsessive-compulsive disorder
Clinical feature
Cognitive function
