一种丙酮酸乙酯微囊的制备方法

The preparation of microencapsulating ethyl pyruvate

对丙酮酸乙酯进行微囊化研究,经过对比丙酮酸乙酯的包埋率确定最适的选材及条件,并对其各项性能指标进行测定。对制备的丙酮酸乙酯微囊进行喷雾干燥,得到丙酮酸乙酯微囊粉末。实验结果表明,最适壁材组合是阿拉伯胶与Hi-cap 100,壁材与水的最佳质量比例是1.5∶1,最佳喷雾干燥条件进风口温度为160℃,出风口温度为80℃。经过高效液相色谱检测丙酮酸乙酯微胶囊粉末包埋量29.4%,包埋率98%,微囊粉末表面光滑,无塌陷无裂缝,微囊符合要求。

The optimum materials and conditions were studied for the microencapsulation of ethyl pyruvate by comparing the encapsulation rate of the microcapsules. The best results were obtained when gum arabic and Hi-cap 100 were used as shell materials, the ratio of shell materials and water was 1.5： 1, the best inlet air temperature was 160 ℃ and outlet air temperature was 80 ℃. Content determination of microencapsuled ethyl pyruvate powder by RP-HPLC. Content of microencapsuled ethyl pyruvate was 29.4% and encapsulation rate was 98%. Microencapsulated powder surface was smooth, no collapse, no cracks, micro-capsules to meet the requirements.