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MiR-26a在垂体腺瘤中表达的研究 被引量：1

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摘要 垂体腺瘤为颅内常见肿瘤，约占颅内肿瘤的10％。微小RNA（miRNAs）是一种能够调节蛋白质编码基因表达的非编码的小RNA，成熟的miRNA由21～23个核苷酸所组成，能够识别靶mRNA序列并与其结合，负性调节基因的表达。在过去的几年中，人们对miRNA与肿瘤的关系有了越来越多的了解。本研究应用Real—time PCR的方法检测垂体腺瘤中miR-26a的表达情况，意在为明确垂体腺瘤的发病机制、寻找可靠的治疗靶点提供新思路。
作者 孙鹏鹏 王雪峰 赵鑫 刘晓谦 王智 岳武
机构地区 哈尔滨医科大学附属第四医院神经外科
出处 《中华神经外科杂志》 CSCD 北大核心 2011年第9期882-884,共3页 Chinese Journal of Neurosurgery
关键词 垂体腺瘤 miRNA 颅内肿瘤 MRNA序列 调节基因 小RNA 基因表达 REAL
分类号 R736.4 [医药卫生—肿瘤]
  • 相关文献

参考文献12

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二级参考文献28

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共引文献36

同被引文献10

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中华神经外科杂志
2011年 第9期

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