组织型纤溶酶原激活剂对神经血管单元功能影响的研究进展
被引量:2
摘要
组织型纤溶酶原激活剂(tPA)是体内重要的丝氨酸蛋白激酶,已被美国FDA批准用于急性缺血性脑卒中超早期溶栓治疗。tPA也在神经血管单元中广泛表达,通过与不同细胞表面受体相互作用介导细胞信号传导,在不同的病理过程中发挥重要作用,影响神经元、胶质细胞和血脑屏障的功能。本文就近年来该领域的研究进展做一综述。
出处
《国际神经病学神经外科学杂志》
2011年第4期334-337,共4页
Journal of International Neurology and Neurosurgery
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