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亚急性硬化性全脑炎诊治进展 被引量:2

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摘要 亚急性硬化性全脑炎是由有缺陷的麻疹病毒持续中枢神经系统感染引起的,麻疹病毒M基因的变异是导致持续感染的重要原因。特征性的病理表现为核内包涵体。通常以轻微智力下降为首发症状,最具特征的表现是节律性肌阵挛,晚期大脑皮质功能几乎完全丧失,最后因循环衰竭或继发感染而死亡。实验室检查表现为脑脊液和血清麻疹抗体滴度升高,脑电图显示周期性复合波。该病目前无疗效肯定且持久的疗法,脑室内注射IFN-α联合口服异丙肌苷是目前最有效的方法。
作者 马艳 杜怡峰
出处 《国际神经病学神经外科学杂志》 2011年第4期356-360,共5页 Journal of International Neurology and Neurosurgery
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参考文献23

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二级参考文献49

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