外斜儿童多焦视觉诱发电位特征性变化

Characteristic changes of multifocal visual evoked potential in exotropias

目的研究外斜儿童多焦视觉诱发电位的特征性变化。方法采用德国Roland公司生产的RETIScan3.20多焦视觉电生理仪,对103例外斜患儿和30名正常对照组儿童进行多焦视觉诱发电位的检测,进行视网膜不同区域的比较。结果外斜组特征峰的振幅反应密度第1环为(710.31±13.54)nV·deg-2,低于正常对照组(835.29±11.02)nV·deg-2;外斜组特征峰隐含值第1环为(109.9±10.8)ms,长于正常对照组(103.8±11.1)ms,两者差异有统计学意义(P<0.05)。外斜组颞侧视网膜特征峰隐含值(106.9±3.1)ms,长于正常对照组(102.3±2.1)ms,两者差异有统计学意义(P<0.05);外斜组下半侧视网膜特征峰隐含值(108.6±3.4)ms,长于正常对照组(106.4±2.2)ms,两者差异有统计学意义(P<0.05)。结论外斜组的视觉传导通路的损害中心重于周边。外斜患者颞侧视网膜、下半视网膜视神经传导通路有损害。外斜的机能及形态学异常可能存在于从神经节细胞到视皮层的整个通路中,而不是单独某个层面受损。

Objective To study the characteristic changes of multifocal visual evoked potential（mVEP） in exotropic children.Methods The mVEP of both eyes of 103 exotropic children and 30 normal control children were recorded by Roland RETIScan 3.20 multiofcal electrophysiological system made by Germany Roland company,the changes in different retinal area were compared.Results The amplitude density in the first eccentricitie of the exotropia group was about（710.31±13.54）nV·deg-2,was lower than that of normal group（835.29±11.02）nV·deg-2;The implicit value in the first eccentricitie of the exotropia group was about（109.9±10.8）ms,was longer than that of the normal group（103.8±11.1） ms,there was statistical differences.The implicit value in the temporal retinal hemifield of exotropia group was about（106.9±3.1） ms,was longer than that of normal group（102.3±2.1） ms,there was statistical difference（P0.05）.The implicit value in the lower retinal hemifield of exotropia group was about（108.6±3.4） ms,was longer than that of normal group（106.4±2.2） ms,there was statistical difference（P0.05）.Conclusions In the exotropia group,the damage of visual conduction pathway in the central filed is more serious than that in the periphery filed.There are some damages in temporal and lower retinal field of visual conduction pathway in the exotropia group.In the exotropic eyes,the disfunction and morphology disorder may be existed though the full visual pathway from the ganglion cells to the visual cortex,but not a solo lamina.