期刊文献+

核苷酸类似物治疗慢性乙型肝炎的长期管理和面临的挑战 被引量:4

下载PDF
导出
摘要 最近10年来,口服核苷类似物(NAs)的应用使慢性乙型肝炎(CHB)治疗取得了重大进展。许多研究表明NAs可以有效地抑制CHB患者体内HBV DNA复制,从而延缓甚至阻断疾病进展。
作者 陈成伟
出处 《肝脏》 2011年第4期279-282,共4页 Chinese Hepatology
  • 相关文献

参考文献20

  • 1贾继东,李兰娟.慢性乙型肝炎防治指南(2010年版)[J].肝脏,2011,16(1):2-16. 被引量:208
  • 2Chang TT, Liaw YF, Wu SS, et al. Long term entecavir therapy results in the reversal of fibrosis cirrhosis and continued histological improvement in patients with chronic hepatitis B. Hepatology, 2010, 521 886-893.
  • 3European Association for the Study of the Liver. EASL Clinical Practice Guidelines: Management of chronic hepatitis B. J Hepatol, 2009, 50: 227-242.
  • 4Lok AS, McMahon BJ. Chronic Hepatitis B: Update 2009. Hepatology, 2009, 50: 1 -36.
  • 5Liu F, Wang L, Li XY. Poor durability of lamivudine effectiveness despite stringent cessation criteria: A prospective clinical study in hepatitis B e antigen-negative chronic hepatitis B patients. J Gastroenterol Hepatol, 2011, 26: 456- 460.
  • 6Locarnini S. Primary resistance, multidrug resistance, and cross- resistance pathways in HBV as a consequence of treatment failure. Hepatol Int, 2008, 2: 147-151.
  • 7Tenney DJ, Pokorowski KA, Rose RE, et al. Entecavir maintains a high genetic harrier to HBV resistance through 6 years in naive patients. Gastroenterology, 2009, 136(5, Suppl 1): 865A.
  • 8Yokosuka O, Takaguehi K, Fujioka S, et al. Long-term use of entecavir in nucleoside-naive Japanese patients with chronic hepatitis B infection. J Hepatol, 2010, 52: 791-799.
  • 9Snow-Lampart A, Chappell B, Curtis M, et al. No resistance to tenofovir disoproxil fumarate detected after up to 144 weeks of therapy in patients monoinfeeted with chronic hepatitis B virus. Hepatology, 2011, 53: 763-773.
  • 10Dienstag JL. Hepatitis B virus infection. N Engl J Med, 2008,359: 1486-1500.

二级参考文献13

共引文献207

同被引文献33

引证文献4

二级引证文献23

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部