Organocatalyzed Highly Efficient Michael Addition of Malonate Derivatives to α,β-Unsaturated Ketones Using Chiral Schiff Bases
Organocatalyzed Highly Efficient Michael Addition of Malonate Derivatives to α,β-Unsaturated Ketones Using Chiral Schiff Bases
摘要
An efficient enantioselective Michael addition of ethyl-2-cyanoacetate and diethyl malonate to α,β-unsaturated ketones catalyzed by a simple chiral Schiff base, and products were obtained in good yields at room temperature.
基金
We appreciate the National Natural Science Foundation of China （No. 20962018, 20862015, 20762009 and 20562011） for supporting this research.
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