卡孕栓治疗产后、手术后尿潴留和腹胀72例临床分析

Effect of methyl carboprost suppository on urinary retention and abdominal distention after childbirth and surgery

目的:探讨卡孕栓治疗产后和妇产科手术后尿潴留和腹胀气临床效果和起效时间。方法:选择我院2008年5月～2010年7月收治的144例产后和手术后尿潴留和腹胀气患者,分为两组,每组72例,卡孕栓组给予卡孕栓1mg纳入肛门内3～4cm深处;新斯的明组给予新斯的明1mg肌肉注射,比较两组患者用药后疗效和起效时间。结果:卡孕栓组显效55例(76.39%),有效13例(18.06%),无效4例(5.55%);新斯的明组显效58例(80.56%),有效11例(15.23%),无效3例(4.21%),两组显效率和有效率均无明显差异(P>0.05)。卡孕栓组药物起效时间0～30、30～60、>60min分别为87.50%、6.94%、5.56%,新斯的明组分别为15.28%、80.56%、4.16%,卡孕栓组药物起效时间明显快于新斯的明组(P<0.01)。结论:卡孕栓可用于治疗产后、手术后尿潴留和腹胀,能缩短尿潴留和腹胀时间,有利于患者产后和术后恢复,使用方便、经济、安全,疗效较好,可推广使用。

Objective. To explore the effect of methyl carboprost suppository on urinary retention and abdominal distention after childbirth and surgery. Methods= A total of 144 cases with urinary retention and abdominal distention after childbirth and surgery postpartum and surgery, who were admitted from May 2008 to July 2010 were selected and randomly divided into two groups by half methyl carboprost suppository group with methyl carboprost suppository 1 mg and neostigmine group with intramuscular injeetion of neostigmine 1 mg. The efficacy and onset time were observed and compared. Results There were 55 cases with marked effect （76.39%）, 13 effective cases （18.06%） and 4 ineffective cases （5.55%） in methyl carboprost suppository group; while there were 58 cases with marked effect （80.56%）, 11 effective cases （15. 23%） and 3 ineffective cases （4. 21%） in neostigmine group. There was no significant difference in marked efficacy and efficacy （P〉0.05）. The efficacy was 87.50%, 6.94%, 5.56% for 0-30, 30-60 and ~ 60 rain, respectively in methyl carboprost suppository group; while 15. 28%, 80. 56%, 4.16% for 0-30, 30-60 and 〉60 min, respectively in neostigmine group. There were significantly more effective cases during 0-30 and 30-60 rain in methyl carboprost suppository group（P〈0.01）. Oonolusion. Methyl carboprost suppository can shorten the treatment time of urinary retention and abdominal distention, and is useful for patients rehabilitation. It is convenient, economical, safe and effective. It is worthy extensive clinical application.