肿瘤标志物CEA在乳腺癌中的应用

Application of tumer marker CEA in Breast cancer

目的探讨血清中CEA浓度对乳腺癌的诊断和预后评估价值。方法用免疫化学发光法检测97例乳腺癌、74例乳腺增生和50例正常对照组的血清CEA浓度,评价其对乳腺疾病的诊断和预后判断价值。结果以CEA>15ng/mL时为判断上限时,其诊断阳性率为17.5%且随着疾病恶性程度的升高,CEA浓度可明显增高;另外,CEA浓度与乳腺癌的临床分期有一定的关系。结论检测血清CEA浓度有助于乳腺癌的诊断和预后判断。

Objective To study concentration of CEA in patient＇s serum to the diagnostic and prognosis value of breast cancer.Methods To detect the concentration of serum CEA in 97 patients with breast cancer,74 women of Benign Disease and 50 healthy women by applying fully automatic immunoassay of chemiluminescence and to evaluate the diagnostic and prognosis value of CEA to the breast cancer.Results As CEA15ng/mL,its ratio of positive rate was seventeen point five percent;the more serious the disease,the higher the value;there were relations between the concentration of CEA and the periods of tumor of breast cancer.Conclusion Examining the concentration of CEA will be helpful in the diagnostic and prognosis of the breast cancer.