硅胶负载硅钨酸催化合成丁醛乙二醇缩醛

Catalytic synthesis of butyraldehyde glycol acetal by H_4SiW_(12)O_(40)/silica gel

以硅胶负载硅钨酸为催化剂,丁醛和乙二醇为原料合成丁醛乙二醇缩醛。探讨硅胶负载硅钨酸对缩醛反应的催化活性,较系统地研究了醛醇物质的量比、催化剂用量、反应时间等因素对产物收率的影响。实验表明:硅胶负载硅钨酸是合成丁醛乙二醇缩醛的良好催化剂,在固定丁醛为0.2mol,催化剂用量为0.3g,n(丁醛)∶n(乙二醇)=1∶1.5,带水剂环己烷6mL,反应时间45 min的适宜条件下,丁醛乙二醇缩醛的收率可达78.3%.

Butyraldehyde glycol acetal was synthesized from butyraldehyde and glycol in the presence of H4SiW12O40/silica gel as catalyst.The factors influencing the synthesis were discussed and the best reaction conditions were found out.Experimental results showed that H4SiW12O40/silica gel is an excellent catalyst.The optimum conditions are： the quantity of catalyst is 0.3g,molar ratio of butyraldehyde to glycol is 1∶1.5,the volume of cyclohexane as the water-carrying agent is 6 mL,and the reaction time is 45 min,the yield of its can reach 78.3 %.