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DNA修复基因XPC多态性与肺癌易感性关系的meta分析

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摘要 核苷酸切除修复(Nucleotide excision repair,NER)通路是DNA损伤修复机制中一条重要的通路,主要修复由紫外线造成的环丁烷嘧啶二聚体(CPD)、DNA的加合物以及链间交联[1,2]。XPC蛋白是NER通路中最为重要的蛋白之一,该基因最早是在北美和欧洲人群中较为多发的着色性干皮病补群C中被发现的[3],是核苷酸切除修复系统的重要组成成分,
作者 李立明 赵松
出处 《临床肺科杂志》 2011年第11期1758-1761,共4页 Journal of Clinical Pulmonary Medicine
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参考文献15

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