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A Stochastic Model for Protein Synthesis and Activation through RNA-Protein Interaction in BioAmbients Calculus

A Stochastic Model for Protein Synthesis and Activation through RNA-Protein Interaction in BioAmbients Calculus
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摘要 Cells use various RNA (Ribonucleic Acid) regulatory mechanisms in order to temporally and coordinately influence the rate of protein synthesis. A deeper understanding of the dynamics of RNA regulation can ultimately bridge the gap between transcriptional control and protein expression. The nonlinear process of RNA-Protein Interaction (RIP), which can be viewed as the RNA analog of the better-known chromatin immunoprecipitation application (CHIP) plays a crucial role in post-transcriptional regulation of gene expression. While ChIP identifies DNA (Deoxyribonucleic Acid) targets of DNA-binding proteins in their cellular context, RIP can be used to identify specific RNA molecules associated with specific nuclear or cytoplasmic RNA-binding proteins. In this paper, a stochastic model in BioAmbients calculus for the protein synthesis and activation through RIP process is presemed.
出处 《Computer Technology and Application》 2011年第7期565-569,共5页 计算机技术与应用(英文版)
关键词 RNA-protein interaction (RPI) p-calculus stochastic modeling. RNA结合蛋白 蛋白质相互作用 随机模型 进程演算 合成率 激活 DNA结合蛋白 脱氧核糖核酸
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