正常压力脑积水的临床特征和手术治疗

Clinical characteristics and surgical treatment of normal pressure hydrocephalus

目的探讨正常压力脑积水(NPH)的临床特征和手术治疗效果。方法 NPH患者32例,其中17例应用中压分流管、15例用可调压分流管行脑室-腹腔分流术治疗。结果应用可调压分流管分流者的症状改善率为86.7%(13/15),应用中压分流管者为41.2%(7/17),两者相差显著(P<0.01)。结论应用可调压分流管行脑室-腹腔分流是治疗NPH的有效方法。

Objective To study the clinical characteristics,surgical strategy of normal pressure hydrocephalus（NPH） based on our experience.Method The clinical data of 32 patients with NPH who were treated by ventriculo-peritoneal（V-P） shunt were analyzed respectively.Results Of 32 patients,15 received V-P shunt with adjustable valves and 17 with middle pressure and non-adjustable valves.The effective rate（86.7%,13/15） of patients undergoing the adjustable valve shunt was significantly higher than that（42.1%,7/17） in the patients undergoing middle pressure and non-adjustable valve shunt（P 0.05）.Conclusion V-P shunt with an adjustable valve is an effective method to treat normal pressure hydrocephalus.