人工肝血浆置换术治疗重型肝炎疗效观察及护理

Curative Effect and Nursing of Heavy-duty Hepatitis through Artificial Liver Plasma Replacement Therapy

目的 探讨人工肝血浆置换术治疗重型肝炎的疗效.方法 对78名重型肝炎患者进行了185例次人工肝血浆置换治疗,比较其前后临床症状、总胆红素（TBIL）、直接胆红素（DBIL）、凝血酶原时间（PT）、白蛋白（ALB）的变化.结果 与治疗前相比,临床症状减轻,TBIL、IBIL、PT均显著降低,差异有显著性（P＜0.01）,ALB无显著变化（P＞0.05）,存活42例,死亡36例,存活率53.8%.结论 人工肝血浆置换术是治疗重型肝炎病人一种安全、有效的治疗方法,可明显提高病人的存活率.

Objectives To explore the curative effect of heavy-duty hepatitis through artificial liver plasma replacement therapy. Methods Artificial liver plasma exchange treatment has been conducted to 78 heavy-duty hepatitis patients 185 cases or times. Comparing the clinical symptoms, the total bilirubin（TBIL）, direct bilirubin（DBIL）, prothrombin time（PT）, albumin（ALB） changes. Results We find clinical symptoms are reduced, IBIL, PT, TBIL, are significantly reduced （P〈0.01）, ALB （P〉0.05） is not significantly changed, 42 cases live, 36 cases die. The survival rate reaches 53.8%. Conclusion Artificial liver plasma replacement to heavy-duty hepatitis patient treatment is a safe and effective treatment method, which could evidently improve the patient＇s survival rate.