慢性阻塞性肺疾病合并肺栓塞的临床分析

Clinic Analysis of COPD Patients Complicated with Pulmonary Embolism

目的探讨慢性阻塞性肺疾病(COPD)合并肺栓塞(PE)的临床特点.方法回顾性分析2007年1月至2010年6月间共42例COPD合并PE患者的临床资料,与42例单纯COPD临床资料进行对比.结果慢性阻塞性肺疾病合并肺栓塞组胸痛、咯血、发热、胸腔积液和不对称下肢水肿的发生率高,肺动脉压明显升高,与单纯慢性阻塞性肺疾病组比较,差异有统计学意义(P<0.05).结论 COPD合并PE的临床表现常不典型,当COPD患者出现胸痛、咯血、发热、胸腔积液和不对称下肢水肿时要考虑肺栓塞的可能,并尽快选择CT肺动脉成像或核磁共振肺动脉造影进一步确诊.

Objective To investigate the clinic features of chronic obstructive pulmonary disease（COPD）patients complicated with pulmonary embolism（PE）Method The clinical data of 42 COPD patients complicated with PE were retrospectively analyzed and compared with the data of 42 COPD patients.Results In the COPD with PE group,the incidence of chest pain,hemoptysis,fever,pleural effusion and asymmetric leg edema were obviously higher than that of only COPD group,and pulmonary artery pressure was significantly higher in the COPD with PE group（P0.05）.Conclusions The clinical presentation of PE is often atypical in COPD patients.The patients with COPD should be given attention with pulmonary embolism especially when they have symptoms of chest pain,hemoptysis,fever,pleural effusion and asymmetric leg edema.At this time,the computer tomography pulmonary angiography（CTPA）or MRI pulmonary angiography must be examined as soon as possible.