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钙结合蛋白S100A9功能的研究进展 被引量：3

Biological property and research progress of calcium-binding protein S100A9
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摘要 S100A9是钙结合蛋白S100家族的重要成员之一,其功能作用广泛,参与多种生物学过程。本文介绍了S100A9在临床疾病、信号传导通路和药物靶点中相关功能的研究进展,为该蛋白在哮喘、肿瘤等疾病中的进一步应用提供了新的思路。 S100A9 is one of the most important proteins in S100A9 calcium-binding protein family,which owns extensive function and participates in multiple biological processes.The review introduces the functional research progress in the clinical diseases,signal transduction pathways and drug targets,which may provide new clues for its application in the treatment of asthma and cancer.
作者 尹磊淼 张庆华 王宇 徐玉东 杨永清
机构地区 上海中医药大学上海市针灸经络研究所分子生物学(针灸)实验室 上海中医药大学生物芯片上海国家工程研究中心
出处 《复旦学报（医学版）》 CAS CSCD 北大核心 2011年第5期445-448,共4页 Fudan University Journal of Medical Sciences
基金 国家自然科学基金项目项目(30873299,30701123,81001548) 上海市卫生局青年基金项目(2009Y096) 上海高校优秀青年教师科研基金项目(SZY09022) 上海市重点学科建设项目(S30304)
关键词 S100A9 钙结合蛋白 信号传导通路 药物靶点 S100A9 calcium-binding protein signal transduction pathways drug targets
分类号 Q513 [生物学—生物化学]
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参考文献28

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同被引文献62

  • 1张丽君,刘银坤,朱运松.钙结合蛋白S100A6基因的研究进展[J].国外医学（临床生物化学与检验学分册）,2004,25(6):542-544. 被引量：4
  • 2陈霞（综述,李建生（审校）.S100A9蛋白的生物学特性与临床意义[J].国外医学（内科学分册）,2006,33(6):275-276. 被引量：4
  • 3傅建炜,李建宇,邱良妙,林泽燕,尤民生.福建省黄曲条跳甲药剂敏感性的地区差异[J].福建农林大学学报（自然科学版）,2006,35(3):235-238. 被引量：19
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复旦学报（医学版）
2011年 第5期

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