无糖代谢异常史的冠心病患者糖调节受损的临床研究

Investigation of impaired glucose regulation in coronary heart disease patients without abnormal glucose metabolism

目的:探讨无糖代谢异常史的冠心病住院患者的糖代谢异常状况。方法:对无糖代谢异常史的150例冠心病住院患者进行随意餐后2 h血糖和口服葡萄糖耐量试验(OGTT),检测糖代谢状况。结果:无糖代谢异常史的冠心病住院患者中,经OGTT发现糖尿病患病率为21.3%,糖调节受损患病率为36.0%,糖代谢异常患病率为57.3%;单纯检测空腹血糖,将有81.5%糖耐量受损患者和75.0%糖尿病患者被漏诊。结论:无糖代谢异常史的冠心病住院患者中半数以上合并糖代谢异常,大多数需通过OGTT发现糖代谢异常,因此,OGTT应成为心内科无糖代谢异常的门诊、住院患者的常规必检项目。

Objective：To investigate the clinical conditions of glucose metabolism abnormality in inpatients without abnormal glucose metabolism.Methods：Two hours postprandial blood glucose and oral glucose tolerance test（OGTT） were detected in 150 coronary heart disease inpatients without abnormal glucose metabolism.Results：In these inpatients,the prevalence of diabetes,impaired glucose regulation,and abnormal glucose metabolism via OGTT were 21.3%,36.0%,and 57.3% respectively.However,81.5% patients with impaired glucose tolerance and 75.0% patients with diabetes would be missed diagnosed if only via fasting blood glucose.Conclusion：More than half of coronary heart disease inpatients without abnormal glucose metabolism were complicated with abnormal glucose metabolism after OGTT.Therefore,it was reasonable to detect OGTT in outpatients and inpatients in cardiovascular department.