泮托拉唑与奥美拉唑用于预防创伤后应激性溃疡出血

Pantoprazole and omrptsxole in the prevention of post-traumatic stress ulcer

目的:探讨泮托拉唑与奥美拉唑用于预防创伤后应激性溃疡出血的效果。方法:将78例创伤后患者随机分为泮托拉唑组(40例,静脉滴注泮托拉唑60 mg/d)和奥美拉唑组(38例,静脉滴注奥美拉唑40 mg/d)观察两组临床应激性溃疡出血的情况。结果:泮托拉唑、奥美拉唑预防应激性溃疡出血的总有效率分别为97.5%和94.7%,两组间疗效差异无统计学意义(P>0.05)。结论:泮托拉唑、奥美拉唑均有预防创伤后应激性溃疡出血的作用,是预防应激性溃疡的安全、经济、有效的方法。

Objective：To study the effect of pantoprazole and omeprazole in the prevention of post-traumatic stress ulcer bleeding.Methods：78 post-traumatic patients were randomly divided into two groups：pantoprazole group（40 patients,intravenous infusion of pantoprazole 60mg/d） and omeprazole group（38 patients,intravenous infusion of omeprazole 40mg/d）.All the patients were observed in clinical cases of stress ulcer bleeding.Results：The results of pantoprazole and omeprazole in preventing stress ulcer bleeding total effective rates were 97.5% and 94.7%,the difference was not significant（P0.05）.Conclusion：Pantoprazole and omeprazole were effective in preventing post-traumatic stress ulcer bleeding,which were safe,economical and effective ways to prevent stress ulcer bleeding.