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Different frequencies of electroacupuncture and semen coicis decrease glial fibrillary acidic protein expression in rats with hemisection spinal cord injury

Different frequencies of electroacupuncture and semen coicis decrease glial fibrillary acidic protein expression in rats with hemisection spinal cord injury
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摘要 This study established the following groups of rats: a normal group, a sham surgery group, a spinal cord injury model group, a low-frequency electroacupuncture group, a high-frequency electroacupuncture group and a semen coicis group. In all but the normal and sham surgery groups the left half of Tlo was transected. Four hours after model induction, 5-Hz and 100-Hz electroacupuncture were used to stimulate the acupoints I-luantiao (GB 30), Zusan/i (ST 36), Zhiyan9 (DU 9) and Xuanshu (DU 5), or crude extract from semen coicis was intraperitoneally injected, for 8 consecutive weeks. The results indicated that electroacupuncture stimulation and intraperitoneal injection of semen coicis improved the morphology of spinal cord tissue, promoted the recovery of motion-evoked potentials, suppressed glial fibrillary acidic protein expression, and ameliorated motor function in rats with hemisection spinal cord injury. The effects of high-frequency (100 Hz) electroacupuncture ancl semen coicis were significant. This study established the following groups of rats: a normal group, a sham surgery group, a spinal cord injury model group, a low-frequency electroacupuncture group, a high-frequency electroacupuncture group and a semen coicis group. In all but the normal and sham surgery groups the left half of Tlo was transected. Four hours after model induction, 5-Hz and 100-Hz electroacupuncture were used to stimulate the acupoints I-luantiao (GB 30), Zusan/i (ST 36), Zhiyan9 (DU 9) and Xuanshu (DU 5), or crude extract from semen coicis was intraperitoneally injected, for 8 consecutive weeks. The results indicated that electroacupuncture stimulation and intraperitoneal injection of semen coicis improved the morphology of spinal cord tissue, promoted the recovery of motion-evoked potentials, suppressed glial fibrillary acidic protein expression, and ameliorated motor function in rats with hemisection spinal cord injury. The effects of high-frequency (100 Hz) electroacupuncture ancl semen coicis were significant.
出处 《Neural Regeneration Research》 SCIE CAS CSCD 2011年第24期1870-1875,共6页 中国神经再生研究(英文版)
基金 the High-funded Projects of Japan Science and Technology Ministry,No. 343 the National Natural Science Foundation of China,No. 30772838
关键词 ELECTROACUPUNCTURE semen coicis hemisection spinal cord injury traditional Chinese medicine neural regeneration electroacupuncture semen coicis hemisection spinal cord injury traditional Chinese medicine neural regeneration
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