顺尔宁联合舒利迭气雾剂吸入治疗儿童支气管哮喘疗效观察

Singulair Oral Joint Seretide Aerosol Treatment Children with Enbronchial Asthma

目的观察顺尔宁联合舒利迭气雾剂吸入治疗支气管哮喘的疗效,为支气管哮喘治疗方案提供进一步的参考依据。方法 120例支气管哮喘患儿随机分为对照组和治疗组,每组各60例,均给予补液、解痉、抗炎、吸氧等常规治疗。对照组在常规治疗基础上给予布地奈德气雾剂吸入,而治疗组给予顺尔宁,1次/d,睡前温开水送服,同时联合舒利迭气雾剂吸入治疗,对两组的疗效等进行分析。结果对照组总有效率为76.7%,治疗组总有效率为95.0%,两组总有效率比较差异有统计学意义(χ2=8.254,P=0.0062<0.01)。与治疗前比较,两组患儿治疗后FEV1占预计值百分比、PEF占预计值百分比明显增加,且治疗组改善更为明显(P<0.05)。结论顺尔宁联合舒利迭气雾剂吸入治疗支气管哮喘具有协同作用,疗效确切,能明显改善患儿肺功能,值得临床推广。

Objective To observe the Seretide combined Singulair oral inhalation aerosol treatment bronchial asthma, and to provide further reference for bronchial asthma treatment plan . Methods All 120 patients with bronchial asthma were randomly divided into control and treatment groups of 60 patients, two groups were given rehydration, antispasmodic, anti-inflammatory, oxygen and other conventional treatment. Control group was given conventional treatment based on inhaled budesonide aerosol, while the group was treated with Singulair tablets once a day, warm water was going to bed, and inhalation therapy combined Seretide Aerosol, the two groups after treatment were analyzed. Results The total effective rate in control group was 76.7%, the total effective rate in the treatment group was 95.0%, and the total effective rate had statistically significant difference （P 〈 0.01 ）. Compared with before treatment, two groups patients＇ FEV1% predicted, PEF% predicted increased significantly after treatment, and the treatment group was improved more significantly （P 〈 0.05 ）. Conclusion The Seretide combined Singulair Oral inhalation aerosol treatment bronchial asthma is synergistic and effective, and it can significantly improve lung function in patients, and it is worthy of promotion.