普米克令舒等三联雾化吸入辅助治疗儿童支原体肺炎

Pulmicort Respules Trigeminy Atomization Inhalation in Adjuvant Therapy of Children Mycoplasma Pneumonia

目的观察普米克令舒等三联雾化吸入辅助治疗儿童肺炎支原体肺炎的疗效。方法将100例肺炎支原体肺炎患儿随机分成两组:治疗组50例,在常规静脉用阿奇霉素针的基础上加普米克令舒等三联雾化吸入;对照组50例,单用阿奇霉素针静脉治疗;用药后观察疗效、症状体征、IL-4、不良反应等指标。结果治疗组疗效优于对照组(P=0.027);治疗组临床症状消失时间及胸片恢复时间较对照组显著缩短(P<0.01),治疗组3个月后血清IL-4水平明显低于对照组(P<0.01)。结论普米克令舒等三联雾化吸入辅助治疗儿童肺炎支原体感染疗效优于单纯抗炎治疗。

Objective To observe the curative effect of puhnicort respules trigeminy atomization inhalation treating the disease of children mycoplasma pneumonia. Methods All 100 cases with mycoplasma pneumonia were randomly divided into two groups, such as treatment group （ 50 cases ） with intravenous injection of azithromycin adding pulmicort respules trigeminy atomization inhalation and control group （ 50 cases ） only with azithromycin intravenous injection. Then we observed curative effect, symptoms, signs, IL-4 and adverse effect between the two groups after medication. Results The curative effect in the treatment group was much better than the control group （ P=0.027 ）. The treatment group＇ s extinction time of clinical symptoms-signs and sternum recovery time were much shorter than the control group （ P 〈 0.01 ）. And IL-4 level in the treatment group after 3 months was much lower than the control group （P 〈 0.01 ）. Conclusion The curative effect of pulmicort respules trigeminy atomization inhalation treating children mycoplasma pneumonia was much better than the effect of only with antiinflammatory treatment method.