葡萄膜炎患者和健康人血清中抗S抗原抗体的测定

SERUM ANTIBODIES TO BOVINE RETINAL S ANTIGEN IN THE PATIENTS WITH UVEITIS AND HEALTHY SUBJECTS

我们用 ELISA 检查了43例急、慢性前、全葡萄膜炎患者血清中抗 S-Ag 抗体,并以32例健康人作为对照组。结果发现全葡萄膜炎患者组抗 S-Ag 抗体滴度与对照组无显著性差异(P>0.05);而前葡萄膜炎患者组抗 S-Ag 抗体滴度明显低于健康人(0.01<P<0.05),提示健康人血清中存在自然抗 S-Ag 抗体,并对“抗 S-Ag 抗体与葡萄膜炎的关系”进行了讨论,指出自然抗 S-Ag 抗体对机体可能有保护作用。

The antibodies to bovine S-Ag in sera were determined by ELISA in 43 patients with acute or chronic,anterior or panuveitis and in 32 healthy persons as controls.The results showed that the antibodies titers to bovine S-Ag in the patients with panuveitis were not different from those in the controls (P>0.05)Howerer the antibody titers to bovine S-Ag in the patients with anterioir uveitis were significantly lower than those in the controls (0.01<P<0.05).It is suggested that there are naturally occurring antibodies to S-Ag in health persons.The relationship between antibodies to S- Ag and uveitis is discussed.It is indicated that natural antibodies to S-Ag may play a protective role in the healthy subjects.