岱山县179例反流性食管炎患者的临床特点和生活质量分析

Clinical features and quality of life of patients with reflux esophagitis

目的 了解岱山县近两年内镜诊断的反流性食管炎（RE）患者的临床特点和生活质量状况,分析影响患者生活质量的主要因素.方法 收集2009年2月至2011年2月岱山县内镜诊断的RE患者,通过症状量表和生活质量量表（采用SF-36健康调查量表）了解患者的临床特点和生活质量状况,并进行相关因素分析.结果 RE患者中A级和B级患者所占比例较高.性别、吸烟、饮酒以及RE分级对症状评分的影响均无统计学意义（均P ＞0.05）,而患者年龄对症状评分的影响则有统计学意义（P＜0.05）.RE患者在生活质量量表各个维度的积分均有下降,但吸烟、饮酒、年龄、性别以及内镜下分级对生活质量量表综合评分的影响均无统计学意义（均P ＞0.05）,而患病时间、症状量表评分对生活质量量表综合评分的影响则有统计学意义（P＜0.05）.结论 岱山县RE患者程度多较轻,年龄对RE症状的严重程度有显著影响,症状的严重程度和患病时间是影响患者生活质量的主要因素.

Objective To review clinical features and quality of life of patients with reflux esophagitis （RE）. Methods The clinical data of 179 RE patients admitted in 3 hospitals of Daishan from Feb 2009 to Feb 2011 were retrospectively reviewed, the symptoms and quality of life were surveyed with symptoms questionnaire and SF36 form, and the relationships of symptom and quality of life with age, sex and other parameters of patients were analyzed. Results The average score of symptoms questionnaire was 11.03. The symptom scores were related to age of patients （P 〈0.05）, but not to gender, smoking and drinking （P 〉0.05）. All items in SF-36 were decreased in RE patients, especially body pain and emotional role. Gender, smoking, drinking, age and grades on gastroscopy did not have significant influence on SF-36 scores. The scores of symptom questionnaire were closely correlated with SF-36 （P 〈0.05）. Conclusion Age is the most important factor for the severity of symptom, and the duration of disease and severity of symptom have significant effect on the quality of life for RE patients.