兔角膜碱烧伤后角膜微量元素的变化

Changes of Trace Element after Severe Alkali-burned Cornea in Rabbit

以原子吸收光谱法观察了兔眼角膜严重碱烧伤后角膜铜、锌、钙和镁元素含量的变化及实验治疗的影响。结果角膜烧伤后各治疗组(综合治疗组和甲孕酮组)及对照组角膜中各元素含量均显著增加,一般在1～2周时达高峰,与角膜病变过程和程度相一致。讨论了微量元素在碱烧伤角膜的损伤修复过程中的可能作用。

Trace element study and the effects of combined treatment and medroxyprogesterone on rabbit corneal burns were made. Cu, Zn, Ca and Mg in the cornea were determined with an atomic absorption spectrophotometer before and after burning. The concentration of all elements in the burned corneas was increased significantly which was important in the first two weeks and was in accordance with the degree of the corneal ulceration which suggested that the trace elements take a role in the pathological processes.