1988年北京市急性出血性结膜炎病原分离和鉴定

Isolation and Identification of the Virus of the Epidemic of Acute Hemorrhagic Conjunctivitis in Beijing in 1988

报告1988年北京市暴发急性出血性结膜炎,在流行高峰时收集患者眼结膜拭子标本48份(130例),共分离获得37株(77%)病毒,全部毒珠可被抗Coxsackie A 24变种CA24v(EH24型)免疫血清所中和。

An epidemic of acute hemorrhagic conjunctivitis (AHC) broke out in Beijing during July-September 1988. 37(77%) strains were isolated from the 48 conjunctival swabs (130 patients) in cultures of Hela cells at the Eye Clinic of Beijing Tong Ren Hospital. All 37 strains were identified as an antigenic variant of Coxsackie virus A24(CA24v) by a neutralization test with EH24 antiserum obtained from Hokkaido Institute of Public Health, Sapporo. Before 1988, there was no report of an outbreak of AHC due to CA24v. The time of CA24v invasion in China remains to be ascertained.